
There are quite a few business oriented games. Railroad Tycoon, Roller Coaster Tycoon, SimFarm, SimCity, Oolite, these are all games that come to mind immediately. Each has different ways of approaching the business aspects, but each is very powerful in its own way.
For example, Railroad Tycoon requires the player to consider the best way to run the railroad, how to buy and sell in order to maintain a good profit margin, and keep up maintenance.
SimFarm is a tremendous simulation dealing with the troubles and challenges of keeping a farm running.
Oolite is a space trading simulation. I think it is available for Windows. I have it on my Mac iBook. It is a freeware version of a game that was great on the Apple II computers.
There are a lot of others. I think that there are even some good stock market simulations, although I have never pursued any of them.