Newborn immune activation may have long-term negative impact on brain function. Neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep patterns concurrent with increases in epilepsy-like brain activity -- a combination of symptoms common in autism spectrum disorder (ASD) and other developmental conditions. Source 4s.
Lab-grown human cerebellar cells yield clues to autism. Increasing evidence has linked autism spectrum disorder (ASD) with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex (TSC), a genetic syndrome that often includes ASD-like features. Source 2u.
Amygdala neurons increase as children become adults -- except in autism. Researchers have found that typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults. This phenomenon does not happen in people with autism spectrum disorder (ASD). Instead, children with ASD have too many neurons early on and then appear to lose those neurons as they become adults. Source 4q.
Brain development disorders in children linked to common environmental toxin exposures. Exposures of pregnant women and children to common thyroid-hormone-disrupting toxins may be linked to the increased incidence of brain development disorders, according to new research. The review describes how numerous, common chemicals can interfere with normal thyroid hormone actions, which are essential for normal brain development in fetuses and young children, and suggests a need for greater public health intervention. Source 1n.