Niemann-pick Type C1 - Npc1

Niemann-pick Type C1 Npc1 - Psychology, Special Needs, Health - Posted: 18th Jul, 2017 - 10:10am

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Post Date: 18th Jul, 2017 - 10:10am / Post ID: #

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Niemann-pick Type C1 - Npc1

Rare disease clues found in cell's recycling system. Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular 'recycling' system that helps reduce elevated cholesterol and other accumulated fats in the brains and livers of NPC1 patients, which are hallmarks associated with severe neurological problems. Source 1v.

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