Drop in body temperature linked to aging aggravates manifestations of Alzheimer's disease
The drop in body temperature associated with aging could aggravate the main manifestations of Alzheimer's, suggests a study. Although the phenomenon was demonstrated using transgenic mice, researchers believe that the findings are convincing enough to warrant further investigation in humans. Ref. Source 6s.
Experimental Alzheimer's drug reverses genetic changes thought to spur the disease
When given to old rats, the drug, which is known to affect signaling by the neurotransmitter glutamate, reversed many age-related changes that occur in a brain region key to learning and memory. The drug also produced effects opposing those seen in the brains of Alzheimer's patients. Ref. Source 6d.
Failed cancer therapy could fight Alzheimer's
A failed strategy to thwart cancer may find a new life as a therapy for Alzheimer's disease, according to UC San Diego and Harvard scientists. The finding concerns an enzyme once thought to promote cancer and efforts to inhibit it. Ref. Source 5b.
Heme, a poisonous nutrient, tracked by 'Green Lantern' sensor
The toxin heme is essential to life, but cells must make use of it sparingly and carefully, as poor heme management can lead to Alzheimer's, heart disease and cancer. Researchers tailored ratiometric sensors to tracks heme's movements in yeast cells for the first known time. Ref. Source 2a.
New insight into how Alzheimer's disease begins
A new study offers important insight into how Alzheimer’s disease begins within the brain. The researchers found a relationship between inflammation, a toxic protein and the onset of the disease. The study also identified a way that doctors can detect early signs of Alzheimer’s by looking at the back of patients’ eyes. Ref. Source 2m.