You can overcome depression by doing things that make you happy. For clinical depression you need to see a professional because that will requires someone outside of your box to show you a better way because you cannot see it on your own.
Brain signature of depressed mood unveiled in new study. New research has identified a common pattern of brain activity that may be behind low mood feelings, particularly in people who have a tendency towards anxiety. The newly discovered network is a significant advance in research on the neurobiology of mood, and could serve as a biomarker to help scientists developing new therapies to help people with mood disorders such as depression. Source 9n.
It is very easy to become depressed if you are not positively motivating yourself each day. It is even harder if you are in a negative environment.
Clues to brain changes in depression. In new pre-clinical research, scientists at the University of Maryland School of Medicine (UMSOM), led by Scott Thompson, PhD, Professor of Physiology, have identified changes in brain activity linked to the pleasure and reward system. Source 5y.