How a lethal type of bacteria spreads resistance to antibiotics. Infection by S. Aureus is a serious threat in hospitals worldwide. Now, scientists have identified a key component of the machinery that allows Staphylococcus aureus to transfer genes that confer antibiotic resistance. Halting the spread of resistant bacterial strains is one of the strategies available to tackle hospital infections. Source 2x.
If we can find a way to halt or reverse the resistance bacteria are acquiring to our antibiotics we'll help thousands of people. Resistant bacteria are definitely a plague we've brought on ourselves by over-prescribing drugs and then not taking them all as prescribed.
Antibiotics found to weaken body's ability to fight off disease. Adding another reason for doctors to avoid the overuse of antibiotics, new research shows that a reduction in the variety of microbes in the gut interferes with the immune system's ability to fight off disease. Source 7b.
Newly emerged superbug discovered. Scientists have discovered a newly emerged superbug, hyper-resistant and hypervirulent Klebsiella pneumoniae, which may cause untreatable and fatal infections in relatively healthy individuals and will pose enormous threat to human health. Source 3k.
Antibiotics may reduce the ability of immune cells to kill bacteria. A new study has shown that antibiotics can reduce the ability of mouse immune cells to kill bacteria, and that changes to the biochemical environment directly elicited by treatment can protect the bacterial pathogen. Source 5n.
Potential weapons for the battle against antibiotic resistance discovered. The bacterium Pseudomonas aeruginosa can produce specific molecular factors that dramatically increase or decrease an antibiotic's ability to kill Staphylococcus aureus, another bacterium that often co-infects with P. Aeruginosa. The findings point to the possibility of new antibiotics employing these factors to enhance antibiotic susceptibility. Source 7o.
Nanoparticles as a solution against antibiotic resistance? Scientists have succeeded in developing an efficient method to treat mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination. First of all, the active particles need to have a certain size to be able to reach the deeper airways and not to bounce off somewhere else before. Ultimately, they have to penetrate the thick layer of mucus on the airways as well as the lower layers of the bacteria biofilm. Source 5k.