Malaria vaccine protects adults for up to a year, new study finds
Malaria infects hundreds of millions of people every year, and kills more than half a million, most of them under the age of 5 years. There is no vaccine. But now, a new study has found that an experimental malaria vaccine protected adults from infection for more than a year. Ref. Source 5f.
Malaria: A genetically attenuated parasite induces an immune response
With nearly 3.2 billion people currently at risk of contracting malaria, scientists have experimentally developed a live, genetically attenuated vaccine for Plasmodium, the parasite responsible for the disease. By identifying and deleting one of the parasite's genes, the scientists enabled it to induce an effective, long-lasting immune response in a mouse model. These findings were published in the Journal of Experimental Medicine on July 18, 2016. Ref. Source 5b.
Plasmodium falciparum malaria parasite. Modified experimental vaccine protects monkeys from deadly malaria. Researchers have modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite. In three of the remaining four monkeys, the vaccine delayed when parasites first appeared in the blood by more than 25 days. Ref. Source 3g.
This is a pretty big thing in much of the world. In most third world nations and even in some developing nations malaria is a scourge that causes hundreds of thousands of deaths a year. Saving 50% immediately and providing time to treat 75% of the remaining people is a pretty big deal. That's 87.5%... Huge.
Edited: Abnninja on 23rd May, 2017 - 9:06pm
Proposed cuts to US Malaria Initiative could mean millions more malaria cases. Cutting the budget of the President's Malaria Initiative (PMI) by 44 percent, as the US Congress has proposed, would lead to an estimated 67 million additional cases of malaria over the next four years, according to a mathematical model. Source 3l.
New research agenda to accelerate malaria elimination, eradication. Over 180 scientists, malaria program managers and policy makers from around the world have come together through a consultative process to update the research agenda for malaria elimination and eradication, first produced in 2011. The outcome is a series of seven 'malERA Refresh' papers. This forward-looking research and development agenda should help accelerate progress towards a malaria-free world. Source 3a.
Dye kills malaria parasites at speed not seen before. Research shows that the dye methylene blue is a safe antimalarial that kills malaria parasites at an unprecedented rate. Within two days, patients are cured of the disease and no longer transmit the parasite if they are bitten again by a mosquito. Source 1p.