Neuromyelitis Optica - Nmo

Neuromyelitis Optica Nmo - Psychology, Special Needs, Health - Posted: 19th Jan, 2018 - 8:41pm

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Devic's disease
Post Date: 19th Jan, 2018 - 8:41pm / Post ID: #

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Neuromyelitis Optica - Nmo

Efficacy of antibody targeting Devic's disease proven in new animal model. Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Researchers recently established a localized NMO rat model by injecting NMO-IgG into the spinal cord, and assessed the efficacy of anti-repulsive guidance molecule-a (RGMa) antibody in treating NMO. They found anti-RGMa antibody delayed the onset and attenuated the severity of clinical symptoms of NMO, suggesting that humanized anti-RGMa antibody is a potentially valid therapeutic approach for NMO. Source 8o.

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