Scientists find gender-distinct circuit for depression. Depression affects women nearly twice as much as men, but unraveling the brain's blueprint that regulates this behavior, let alone identifying specific molecular differences between sexes, has proven difficult. Researchers, however, have found and flipped a switch in the brain, revealing a single circuit in mice that activates during stress and is controlled by testosterone. Source 9l.
I really find this hard to believe. Coming from a male that has been dealing with depression for several years, I can state atleast for myself it gets pretty bad sometimes. I would say that it seems like more women tend to be depressed compared to the amount of males, atleast in my personal experiences.