Retinoid therapy may improve vision in people with rare genetic disorder. Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers documented the natural history of vision impairment in patients and identified the cell mechanism behind progressive vision loss. Based on these findings, the team was able to test a retinoid therapy that improved vision in mice with Usher syndrome. The researchers said assessing a similar therapy should now be considered in people with Usher syndrome to see if this therapy might slow vision loss. Source 3o.