The most interesting piece to this I found was when they mentioned that when they tested MAOIs, EST, and Tricyclics that they got the same result. The interesting piece was that some people do not respond to one treatment, but do respond to another and that is saying that the chemistry finds them all to be about the same, or to have about the same result. I'm wondering how much "free will" comes into play where the routes are being discussed. Is there such a social stigma on EST that one might "think" themselves to fail with it? Or the same question for medicines.
A recent study shows that when marijuana is used in low doses, it actually improves depression. However, if marijuana is used in high doses, it can worsen symptoms of depression. Here are more details on this report Source
What are your views on this?
New treatment can alleviate major depression
Machine offers hope for patients not helped by therapy or medication
But a new treatment now available at the University of Utah Neuropsychiatric Institute looks to provide new hope for patients like Pudoff-Oyen, who haven't found relief from their depression using medication. Ref. Source 9
Depression is driven by networks of genes that span brain circuits, study suggests
Depression is a disorder that involves changes in coordinated networks of hundreds of genes across key brain circuits, according to a study. Researchers show through their work how tweaking gene networks can affect susceptibility to depression. Ref. Source 4s.
Many adults who screen positive for depression don't receive treatment
A new study suggests gaps exist in the treatment of depression with many individuals who screen positive for the mental health disorder not receiving treatment, according to a new article. Ref. Source 6u.
The heterogeneous nature of depression
Depression is generally considered to be a specific and consistent disorder characterized by a fixed set of symptoms and often treated with a combination of psychotherapy and medication. However, the standard rating scales used by healthcare professionals and researchers to diagnose this disease often differ in the symptoms they list, perhaps explaining why a one-size-fits-all treatment has to date been so ineffective, new research suggests. Ref. Source 9v.